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  <titleInfo>
    <title>Methodological challenges in biomedical HIV prevention trials</title>
  </titleInfo>
  <name type="personal">
    <namePart>Lagakos, Stephen W.</namePart>
  </name>
  <name type="personal">
    <namePart>Gable, Alicia.</namePart>
  </name>
  <name type="corporate">
    <namePart>Institute of Medicine (U.S.)</namePart>
    <namePart>Committee on the Methodological Challenges in HIV Prevention Trials.</namePart>
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  <name type="corporate">
    <namePart>Institute of Medicine (U.S.)</namePart>
    <namePart>Board on Global Health.</namePart>
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  <name type="corporate">
    <namePart>National Academies (U.S.)</namePart>
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    <publisher>National Academies Press</publisher>
    <dateIssued>c2008</dateIssued>
    <dateIssued encoding="marc">2008</dateIssued>
    <issuance>monographic</issuance>
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  <language>
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    <extent>xi, 258 p. : ill. ; 23 cm.</extent>
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  <abstract>"This IOM committee was formed at the request of the Bill &amp; Melinda Gates Foundation and charged with addressing methodological challenges in late-stage nonvaccine biomedical HIV prevention trials with a specific focus on microbicide and pre-exposure prophylaxis trials."</abstract>
  <note type="statement of responsibility">Committee on the Methodological Challenges in HIV Prevention Trials, Board on Global Health ; Stephen W. Lagakos and Alicia R. Gable, editors ; Institute of Medicine of the National Academies.</note>
  <note>Includes bibliographical references.</note>
  <note>Also available online.</note>
  <subject authority="lcsh">
    <topic>AIDS (Disease)</topic>
    <topic>Prevention</topic>
  </subject>
  <subject authority="mesh">
    <topic>HIV Infections</topic>
    <topic>prevention &amp; control</topic>
  </subject>
  <subject authority="mesh">
    <topic>Clinical Trials as Topic</topic>
  </subject>
  <subject authority="mesh">
    <topic>Program Evaluation</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Anti-Infective Agents</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="mesh">
    <topic>Anti-Retroviral Agents</topic>
    <topic>therapeutic use</topic>
  </subject>
  <classification authority="lcc">RA643.83 .M48 2008</classification>
  <classification authority="ddc" edition="22">362.196/9792</classification>
  <identifier type="isbn">0309114306 (pbk.)</identifier>
  <identifier type="isbn">9780309114301 (pbk.)</identifier>
  <identifier type="lccn">2008299718</identifier>
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